Alba Vílchez-Acosta

This study shows that loss of H3K9me3 in adult mice leads to premature aging, characterized by reduced lifespan, frailty, and accelerated epigenetic aging.

This study shows that partial reprogramming of dentate gyrus neurons in mice improves memory and learning in aged animals.

This study induces in vivo reprogramming in C. elegans and finds it leads to heterogeneous effects on lifespan depending on developmental stage.

This study compares mouse strains for in vivo reprogramming to develop safer strategies and create a comprehensive atlas of reprogrammable strains.

This study shows that continuous in vivo reprogramming with OSKM causes hepatic and intestinal failure, leading to premature death, but a new mouse strain reduces these effects.

This study investigates how adult-specific Reelin expression affects striatal neuronal organization and its implications for neuropsychiatric disorders using mouse models.