Author

Alessandra Ruggiero

Medical University of South Carolina

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:yeast· 1

Frequent Co-Authors

George S. HannaiD· 1 shared Mark T. HamanniD· 1 shared Natalie SainiiD· 1 shared Piotr A. MieczkowskiiD· 1 shared Samuel BeckeriD· 1 shared Sriram VijayraghavaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperGenetics

George S. HannaORCID

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1 paper

Recent·Most cited

Methylglyoxal mutagenizes single-stranded DNA via Rev1-associated slippage and mispairing

Sriram Vijayraghavan, Alessandra Ruggiero, Samuel Becker, Piotr A. Mieczkowski, George S. Hanna, Mark T. Hamann, Natalie Saini

This study shows methylglyoxal mutagenizes single-stranded DNA through Rev1-mediated slippage and mispairing, with mutations enriched in tumor datasets.

Nucleic Acids Research · Jul 19, 2025Peer-reviewedGenetics