Natalie Saini

This study shows that replication-associated single-stranded DNA increases formaldehyde-induced mutagenesis through specific repair pathways.

This study shows methylglyoxal mutagenizes single-stranded DNA through Rev1-mediated slippage and mispairing, with mutations enriched in tumor datasets.

This study identifies DNA repair pathways that prevent acetaldehyde-induced mutagenesis in yeast and corroborates findings in human liver cancers.

This study shows acetaldehyde causes strand-biased G[->]T mutations on single-stranded DNA via Polζ bypass and identifies a unique mutation signature in alcohol-related cancers.

The paper compares mutation spectra between hypermutated rubella virus genomes and SARS-CoV-2 genomes, finding similarities in mutation patterns and suggesting shared mutation mechanisms.