Stab Wound Injury Elicits Transit Amplifying Progenitor-like Phenotype in Parenchymal Astrocytes
Priya Maddhesiya, Finja Berger, Christina Koupourtidou, Alessandro Zambusi, Klara Tereza Novoselc, Judith Fischer-Sternjak, Tatiana Simon, Cora Olpe, Sebastian Jessberger, Magdalena Götz, Jovica Ninkovic
This study identifies injury-induced plastic astrocytes in mice that exhibit self-renewal and neurosphere-forming capabilities, resembling transit-amplifying progenitors in transcriptional profile.
bioRxiv · Sep 10, 2024 · PreprintNeuroscience