Genetically encoded fluorescent reporter for polyamines
Pushkal Sharma, Colin Y. Kim, Heather R. Keys, Shinya Imada, Alex B. Joseph, Luke S. Ferro, Tenzin Kunchok, Rachel Anderson, Yulin Sun, Ömer H. Yilmaz, Jing‐Ke Weng, Ankur Jain
This paper introduces a genetically encoded fluorescent reporter for real-time measurement of polyamine levels in single cells and identifies a link between mitochondrial respiration and polyamine import in Parkinson's disease.
Nature Communications · May 27, 2025Peer-reviewedCell Biology