Author

Malte Sgodda

Medizinische Hochschule HannoverORCID 0000-0002-3945-1517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:organoid / primary culture· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Tobias CantziD· 2 shared Alex Bastianelli· 1 shared Amelie StalkeiD· 1 shared Annika BehrendtiD· 1 shared Björn Hartleben· 1 shared Carola DrögeiD· 1 shared Emma Wang· 1 shared Eva-Doreen Pfister· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Tobias CantzORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 9, 2026

Liver biopsy confirms precise and efficient correction of SERPINA1 after in vivo Base Editing in a Patient with Alpha-1 Antitrypsin Deficiency

Simon Alexander Krooss, Taihua Yang, Qinggong Yuan…·Michael Ott

Liver biopsy after PI*ZZ gene correction therapy reveals efficient and accurate base editing.

DOI 10.64898/2026.06.01.26354551

humanDNA methylation

𝕏 PostBluesky

PhysiologybioRxivPreprintFeb 8, 2024

Impaired transitioning of the FXR ligand binding domain to an active state underlies an FXR-associated PFIC phenotype

Annika Behrendt, Alex Bastianelli, Jan Stindt…·Holger Gohlke

This study identifies a missense variant in FXR that impairs its conformational transition to an active state, leading to reduced BSEP expression and a PFIC phenotype.

DOI 10.1101/2024.02.08.579530

humanorganoid / primary culture

𝕏 PostBluesky