The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment
Luis Enrique Sastré-Velásquez, Alex Dallemulle, Alexander Kühbacher, Clara Baldin, Laura Alcázar‐Fuoli, Anna Niedrig, Christoph Müller, Fabio Gsaller
This study investigates how A. fumigatus expels fluoropyrimidines, reducing antifungal activity and creating a toxic environment for both fungal and mammalian cells.
PLoS Pathogens · Dec 27, 2022Peer-reviewedMolecular Biology