Fabio Gsaller

This study shows that tRNA hypomodification in Aspergillus fumigatus leads to 5-fluorocytosine resistance through premature activation of a cross-pathway control system.

This study investigates how A. fumigatus expels fluoropyrimidines, reducing antifungal activity and creating a toxic environment for both fungal and mammalian cells.

The paper investigates the regulatory motifs in the cyp51A promoter of Aspergillus fumigatus that contribute to azole resistance, revealing iron-dependent and -independent roles of transcription factors.

This paper introduces a novel genetic engineering method using endogenous pyrimidine salvage pathway genes as selectable markers for targeted DNA insertion in fungal pathogens.