Christoph Müller

This study identifies a carbonic sensing pathway (CSP) in Candida auris that enhances drug resistance and skin colonization through mechanisms involving ROS response, cell wall remodeling, and energy metabolism.

The paper identifies ergosterol depletion in Nakaseomyces glabratus as a mechanism for amphotericin B resistance without fitness or virulence defects.

This study identifies eburicol accumulation as the mechanism by which azoles exert fungicidal effects against Aspergillus fumigatus, distinct from their action in yeasts.

This study investigates how A. fumigatus expels fluoropyrimidines, reducing antifungal activity and creating a toxic environment for both fungal and mammalian cells.