Author

Alex Fower

Mary Lyon Centre at MRC Harwell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Abdel AyadiiD· 1 shared Adam CaulderiD· 1 shared Alasdair J. AllaniD· 1 shared Allan BradleyiD· 1 shared Amie Creighton· 1 shared Angelina Gaspero· 1 shared Ann‐Marie MalloniD· 1 shared Antonella Galli· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Abdel AyadiORCID

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1 paper

Recent·Most cited

Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines

Hillary Elrick, Kevin A. Peterson, Brandon Willis, Denise Grant Lanza, Elif Fidan Acar, Edward J. Ryder, Lydia Teboul, Petr Kašpárek, Marie‐Christine Birling, David J. Adams, Allan Bradley, Robert E. Braun, Steve D. M. Brown, Adam Caulder, Gemma F. Codner, , Valerie Laurin

The paper analyzes 3,313 genetically engineered mouse lines to identify gene essentiality as the main factor affecting Cas9-based genome editing success.

Scientific Reports · Sep 30, 2024Peer-reviewedGenetics