Apollo-IRE1: A Genetically Encoded Sensor for Live Cell and Multiplexed Imaging of ER Stress
Eric J. Floro, Alex M. Bennett, Romario Regeenes, Huntley H. Chang, Nitya Gulati, Kenneth K. Y. Ting, Jonathan V. Rocheleau
Apollo-IRE1 is a genetically encoded sensor that detects ER stress by measuring IRE1 oligomerization and fluorescence anisotropy changes, enabling multiplexed imaging in living cells.
bioRxiv · Mar 24, 2026 · PreprintBioengineering