Correspondence of fentanyl brain pharmacokinetics and behavior measured via engineering opioids biosensors and computational ethology
Anand K. Muthusamy, Matthew Rosenberg, Charlene H. Kim, Alex Z. Wang, Haruka Ebisu, Theodore M. Chin, Ashil Koranne, Jonathan S. Marvin, Bruce N. Cohen, Loren L. Looger, Yuki Oka, Markus Meister, Henry A. Lester
This study develops a fluorescent opioid biosensor to measure fentanyl levels in mice and links pharmacokinetics to behavioral patterns using computational ethology.
bioRxiv · Mar 15, 2024 · PreprintNeuroscience