Theodore M. Chin

The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.

The paper identifies TREM2-expressing macrophages as predictors of response to PD-1 blockade in HCC patients using clinical and spatial transcriptomic data.

This study develops a fluorescent opioid biosensor to measure fentanyl levels in mice and links pharmacokinetics to behavioral patterns using computational ethology.

This study shows that gut bacteria influence Huntington's disease progression in Drosophila models, with antibiotics and compounds like crocin reducing disease symptoms while E. coli worsens them.