Author

Alexander D. Friedman

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

Henry H. YiniD· 4 shared Glenn D. R. WatsoniD· 2 shared Konstantin I. BakhuriniD· 2 shared Namsoo KimiD· 2 shared Bryan Lu· 1 shared Charles T. Shoemaker· 1 shared Elijah A. PetteriD· 1 shared Jiwon KimiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersNeuroscience

Henry H. YinORCID

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4 papers

Recent·Most cited

A2A-positive neurons in the nucleus accumbens core regulate effort exertion

Charles T. Shoemaker, Alexander D. Friedman, Bryan Lu, Qiaochu Jiang, Jiwon Kim, Shuangyan Li, Shaolin Ruan, Henry H. Yin

This study shows that A2A-positive neurons in the NAc core regulate effort exertion by bidirectional modulation of lever pressing behavior in an effort-dependent manner.

Journal of Neuroscience · Mar 3, 2025Peer-reviewedNeuroscience

Selective activation of subthalamic nucleus output quantitatively scales movements

Alexander D. Friedman, Henry H. Yin

This study selectively stimulates STN projection neurons in mice and shows that STN output directly controls movement parameters with high precision.

Journal of Neuroscience · Oct 10, 2023Peer-reviewedNeuroscience

Ventral tegmental dopamine neurons control the impulse vector during motivated behavior

Ryan N. Hughes, Konstantin I. Bakhurin, Elijah A. Petter, Glenn D. R. Watson, Namsoo Kim, Alexander D. Friedman, Henry H. Yin

This study shows that VTA dopamine neurons bidirectionally control impulse vector and anticipatory behavior during motivated actions.

Current Biology · May 28, 2020Peer-reviewedNeuroscience

Opponent regulation of action performance and timing by striatonigral and striatopallidal pathways

Konstantin I. Bakhurin, Xiaoran Li, Alexander D. Friedman, Nicholas A. Lusk, Glenn D. R. Watson, Namsoo Kim, Henry H. Yin

This study investigates the roles of striatonigral and striatopallidal pathways in action performance and timing using optogenetic stimulation in mice.

eLife · Apr 23, 2020Peer-reviewedNeuroscience