Konstantin I. Bakhurin

This paper introduces a dual-color miniature endoscope for simultaneous calcium imaging of two neuronal populations in behaving mice, revealing direction-dependent activity patterns in striatal neurons.

This study identifies a cortical circuit involving ACC-D1+ neurons critical for initiating goal-directed movements and shows its therapeutic potential in Parkinsonian akinesia.

This study identifies modular striatal dynamics and reciprocal inhibition in mice performing a water-reaching task, showing how these mechanisms coordinate sequential actions.

This study identifies distinct VTA GABA neurons that regulate force vectors during motivated behavior through precise force tuning and optogenetic manipulation.

This study shows that reducing midline thalamus neuron bursting prevents absence seizures in a mouse model by enhancing vigilance and suppressing seizure activity.

This study shows that phasic dopamine signaling in VTA neurons regulates force exertion during learning, not reward prediction error.

The paper introduces a new system for simultaneous calcium imaging and optogenetic stimulation in freely moving mice, demonstrating its ability to image and activate specific neurons and recreate behavior.

This study shows that VTA dopamine neurons bidirectionally control impulse vector and anticipatory behavior during motivated actions.

This study investigates the roles of striatonigral and striatopallidal pathways in action performance and timing using optogenetic stimulation in mice.

This paper introduces a head-fixation system with load cells to continuously monitor force generated by mice during behavior, revealing previously neglected movement dynamics and correlating them with neural activity.

This study identifies three distinct populations of VTA GABAergic neurons that encode rotational head movements during target pursuit, with their activity disrupted during reward consumption.

This study investigates spatial coding and neural synchronization in epilepsy using in vivo calcium imaging and network modeling, finding impaired spatial processing and desynchronized firing in epileptic mice.