Glenn D. R. Watson

The paper identifies a locus coeruleus-hippocampal dopamine pathway involved in operant reinforcement by showing D1+ dentate gyrus neurons mediate self-stimulation through optogenetic activation.

The paper examines sleep-wake regulatory nuclei in rats using long-term single- and multi-unit recordings, finding differences in activity profiles compared to previous studies when correlated with cortical and behavioral data.

This study shows that VTA dopamine neurons bidirectionally control impulse vector and anticipatory behavior during motivated actions.

This study investigates the roles of striatonigral and striatopallidal pathways in action performance and timing using optogenetic stimulation in mice.

This study identifies three distinct populations of VTA GABAergic neurons that encode rotational head movements during target pursuit, with their activity disrupted during reward consumption.

This study identifies a thalamo-subthalamic pathway involved in movement initiation and shows that stimulating this pathway can rescue Parkinsonian symptoms in mice.

This study identifies a striatal interneuron circuit where parvalbumin-positive fast-spiking interneurons represent target distance and regulate striatal projection neuron activity to modulate movement velocity during pursuit behavior.

This study identifies a hypothalamic-extended amygdala circuit that regulates temporal discounting by modulating motivational signals through AgRP neurons and Y1R activation.

This study demonstrates the feasibility of simultaneously recording calcium and BOLD signals in rats using GCaMP6-based fiber photometry and fMRI, showing reproducible responses to visual stimuli.