Namsoo Kim

This paper introduces a dual-color miniature endoscope for simultaneous calcium imaging of two neuronal populations in behaving mice, revealing direction-dependent activity patterns in striatal neurons.

This study shows that caspase-3 activation is essential for activity-dependent synapse elimination during development and in Alzheimer's disease models.

The paper introduces a new system for simultaneous calcium imaging and optogenetic stimulation in freely moving mice, demonstrating its ability to image and activate specific neurons and recreate behavior.

This study shows that training-induced excitatory synaptogenesis in the ACC->DMS circuit is required for effort control, not learning, and is mediated by the 2{delta}-1 protein.

This study shows that VTA dopamine neurons bidirectionally control impulse vector and anticipatory behavior during motivated actions.

This study investigates the roles of striatonigral and striatopallidal pathways in action performance and timing using optogenetic stimulation in mice.

This study identifies three distinct populations of VTA GABAergic neurons that encode rotational head movements during target pursuit, with their activity disrupted during reward consumption.

This study identifies a striatal interneuron circuit where parvalbumin-positive fast-spiking interneurons represent target distance and regulate striatal projection neuron activity to modulate movement velocity during pursuit behavior.

This study identifies a hypothalamic-extended amygdala circuit that regulates temporal discounting by modulating motivational signals through AgRP neurons and Y1R activation.

This paper identifies a cellular mechanism involving giant ankyrin-B that leads to stochastic axon projections and contributes to neurodiversity and ASD.

This study identifies fast-spiking interneurons in the striatum as key drivers of habitual behavior through circuit-level modulation of spiny projection neurons.