Author

Alexander E. Ferrazzoli

Brandeis University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Organism:yeast· 1

Frequent Co-Authors

Susan T. LovettiD· 2 shared Adam C KaplaniD· 1 shared Brenda R. Lemos· 1 shared David P. WatermaniD· 1 shared Deani L. Cooper· 1 shared James E. HaberiD· 1 shared James Kuo· 1 shared Ji Eun BaeiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Susan T. LovettORCID

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3 papers

Recent·Most cited

DnaA and SspA Regulation of the iraD gene of E. coli: an alternative DNA damage response independent of LexA/RecA

Thalia H. Sass, Alexander E. Ferrazzoli, Susan T. Lovett

This paper identifies an alternative DNA damage response in E. coli regulated by DnaA and SspA, independent of the LexA/RecA SOS response, showing DNA damage induces iraD expression through DnaA repression relief and SspA modulation.

Genetics · Apr 21, 2022Peer-reviewedGenetics

The role of replication clamp-loader protein HolC of Escherichia coli in overcoming replication /transcription conflicts

Deani L. Cooper, Taku Harada, Samia Tamazi, Alexander E. Ferrazzoli, Susan T. Lovett

This study investigates the role of HolC in E. coli by analyzing suppressor mutants, showing it helps resolve replication-transcription conflicts through Rho-dependent termination and DksA function.

mBio · Mar 8, 2021Peer-reviewedGenetics

CRISPR/Cas9 cleavages in budding yeast reveal templated insertions and strand-specific insertion/deletion profiles

Brenda R. Lemos, Adam C Kaplan, Ji Eun Bae, Alexander E. Ferrazzoli, James Kuo, R. Anand, David P. Waterman, James E. Haber

The paper investigates CRISPR-Cas9 cleavage in yeast and human cells, revealing templated insertions and strand-specific indel patterns influenced by gRNA orientation and repair factors.

Proceedings of the National Academy of Sciences · Feb 13, 2018Peer-reviewedMolecular Biology