Author

Alexander G. Heriot

Peter MacCallum Cancer Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andréa ParadisiiD· 1 shared Corina BehrenbruchiD· 1 shared Cyril DégletagneiD· 1 shared Fabien LuiggiiD· 1 shared Frédéric HollandeiD· 1 shared Kristina Radkova· 1 shared Lea Stephan· 1 shared Lisa FrydmaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andréa ParadisiORCID

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1 paper

Recent·Most cited

Netrin-1 regulates colorectal cancer stem cell self-renewal via a TFF3 dependent paracrine survival mechanism

Morgan Brisset, Kristina Radkova, Andréa Paradisi, Mélodie Grandin, Lea Stephan, Robin Wagner, Cyril Dégletagne, Fabien Luiggi, Lisa Frydman, Alexander G. Heriot, Corina Behrenbruch, Tamara M. Vu, Patrick Mehlen, Frédéric Hollande

This study identifies the netrin-1/UNC5B/TFF3 axis as a regulator of colorectal cancer stem cell self-renewal and shows that targeting it with NP137 enhances chemotherapy efficacy in preclinical models.

bioRxiv · Apr 28, 2025 · PreprintCancer Biology