Author

Alexander J. McAdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Microbiology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ahmet Z. Uluer· 1 shared Alexandra J. PoretiD· 1 shared Ashley R. Cross· 1 shared Christina Merakou· 1 shared Georgia K. LagoudasiD· 1 shared Gregory P. PriebeiD· 1 shared Joanna B. GoldbergiD· 1 shared Kathryn E. MansouriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Ahmet Z. Uluer

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1 paper

Recent·Most cited

De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen

Alexandra J. Poret, Matthew Schaefers, Christina Merakou, Kathryn E. Mansour, Georgia K. Lagoudas, Ashley R. Cross, Joanna B. Goldberg, Roy Kishony, Ahmet Z. Uluer, Alexander J. McAdam, Paul C. Blainey, Sara O. Vargas, Tami D. Lieberman, Gregory P. Priebe

This study shows that de novo mutations in Burkholderia dolosa cause phenotypic switching, with O-antigen loss increasing immune cell uptake but reducing lung competitiveness, depending on infection duration and tissue localization.

bioRxiv · Feb 6, 2024 · PreprintMicrobiology