Author

Alexandra J. Poret

ORCID 0000-0002-0723-987XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ahmet Z. Uluer· 1 shared Alexander J. McAdam· 1 shared Ashley R. Cross· 1 shared Christina Merakou· 1 shared Georgia K. LagoudasiD· 1 shared Gregory P. PriebeiD· 1 shared Joanna B. GoldbergiD· 1 shared Kathryn E. MansouriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Ahmet Z. Uluer

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1 paper

Recent·Most cited

De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen

Alexandra J. Poret, Matthew Schaefers, Christina Merakou, Kathryn E. Mansour, Georgia K. Lagoudas, Ashley R. Cross, Joanna B. Goldberg, Roy Kishony, Ahmet Z. Uluer, Alexander J. McAdam, Paul C. Blainey, Sara O. Vargas, Tami D. Lieberman, Gregory P. Priebe

This study shows that de novo mutations in Burkholderia dolosa cause phenotypic switching, with O-antigen loss increasing immune cell uptake but reducing lung competitiveness, depending on infection duration and tissue localization.

bioRxiv · Feb 6, 2024 · PreprintMicrobiology