Multiple roles for TFG ring complexes in neuronal cargo trafficking
Ziheng Zhang, Molly M. Lettman, Amber L. Schuh, Basudeb Bhattacharyya, Peter S. Randolph, Trisha Nandakumar, Ishan Kulkarni, Alexander Roach, James R. Alvin, Diane Gengler, Scott M. Stagg, James L. Keck, Anjon Audhya
This study identifies structural and functional roles of TFG ring complexes in neuronal cargo trafficking, showing how mutations disrupt their stability and contribute to neurodegenerative disease.
bioRxiv · Nov 5, 2024 · PreprintBiochemistry