James L. Keck

The paper presents two primosome structures in Escherichia coli, revealing mechanisms of DNA replication restart and a similarity between DnaT and DnaA.

This study shows DNA damage induces alternative splicing of RIF1, generating isoforms that affect DNA repair complex assembly and phase separation.

This study identifies how altering translation in E. coli mitigates the growth inhibition caused by chemically stabilized G-quadruplexes.

This study identifies structural and functional roles of TFG ring complexes in neuronal cargo trafficking, showing how mutations disrupt their stability and contribute to neurodegenerative disease.

This study identifies genetic interactions linking the PriA/PriB DNA replication restart pathway to double-strand DNA break repair in E. coli using transposon insertion sequencing and targeted experiments.