Functional evaluation of microdissected tumor 'cuboids': a microscale ex vivo cancer model that retains a complex tumor microenvironment
Lisa F. Horowitz, Ricard A. Rodríguez‐Mias, Marina Chan, Songli Zhu, Yin Tang, Alexandra Locke, Noah R. Gottshall, Ivan Stepanov, Casey Stiles, Marcus Yeung, Tran NH Nguyen, Ethan J. Lockhart, Charlotte Ahls, Elizabeth Wayne, Wei Wei, , Albert Folch
The paper develops a microscale ex vivo cancer model using tumor cuboids that retain a complex tumor microenvironment, enabling drug and immunotherapy testing.
bioRxiv · Mar 22, 2024 · PreprintCancer Biology