Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata
Angela Meccariello, Shibo Hou, Serafima Davydova, James D. Fawcett, Alexandra Siddall, Philip T. Leftwich, Flávia Krsticevic, Philippos Aris Papathanos, Nikolai Windbichler
This paper demonstrates the feasibility of using CRISPR-Cas9 gene drives in the medfly to achieve sex conversion and female sterility, offering a strategy for pest population suppression.
Nature Communications · Jan 8, 2024Peer-reviewedSynthetic Biology