Angela Meccariello

The paper develops a split-CRISPR/Cas9 system for sex conversion in Mediterranean fruit flies to improve population control strategies.

This paper demonstrates the feasibility of using CRISPR-Cas9 gene drives in the medfly to achieve sex conversion and female sterility, offering a strategy for pest population suppression.

The paper introduces two computational methods, R-CQ and KAMY, to detect sex chromosome sequences in Tephritid pests and evaluates their performance on chromosome-level assemblies.

The paper engineers sex distortion in Ceratitis capitata using CRISPR/Cas9 and Cas12a to bias sex ratios towards males.

The paper establishes Drosophila models to study two CRISPR/Cas9 sex distortion mechanisms, X-shredding and X-meddling, and their functional differences.

The paper identifies a Y-linked gene, MoY, essential for male sex determination in medflies and shows its conservation across multiple fruit fly species, enabling potential genetic control strategies.

This paper demonstrates efficient CRISPR-Cas9-based gene disruption in the medfly using RNPs, achieving high germline transmission and mutant phenotypes.

The paper characterizes mollusc communities associated with three Cystoseira species in the Gulf of Naples, finding high dominance by Mytilus galloprovincialis and distinct community structures among the algal species.

This study identifies the yellow ortholog as the brown body locus in houseflies using CRISPR-Cas9 and confirms its role in melanization.