RNA promotes MAPK signaling through direct interaction with BRAF
Alexia Le Barch, Sabrina Mennour, Lucilla Fabbri, Titash Sen, Isabelle Girault, Virginie Quidville, Jessica Andréani, Raphaël Guérois, Caroline Robert, Patricia Uguen, Stéphan Vagner
This study shows RNA directly interacts with BRAF to regulate MAPK signaling by facilitating RAF complex formation and MEK1/2 phosphorylation.
bioRxiv · Oct 23, 2026 · PreprintMolecular Biology