Jessica Andréani

This study shows RNA directly interacts with BRAF to regulate MAPK signaling by facilitating RAF complex formation and MEK1/2 phosphorylation.

This paper evaluates AlphaFold3's ability to predict protein-RNA interaction specificity using omics data and structural information, highlighting both its potential and limitations.

The paper identifies a missing component of the ComB T4SS in H. pylori essential for DNA uptake, showing it is a hexameric ATPase interacting with ComB4.

This study identifies a tripartite protein complex essential for ssDNA uptake during natural transformation in firmicutes, validated through structural modeling and experimental assays.

The paper identifies a new AbiF-like system in C. difficile and shows its regulation by a non-coding RNA through RNA-protein interactions.

This study identifies a protein-protein interaction between ComM and DprA that is critical for DprA to recruit ComM to promote recombination during natural transformation in Gram-negative bacteria.

The paper identifies a bifunctional snoRNA, snR107, that guides rRNA modification and scaffolds gametogenesis effectors in fission yeast.

The paper analyzes conservation patterns in protein-RNA interface contacts using structural interologs, finding high conservation of distance-based and apolar contacts but versatility in hydrogen bonds and salt bridges.

The paper demonstrates that AlphaFold2-Multimer can identify interaction sites in intrinsically disordered regions with improved accuracy using fragment-based approaches and evolutionary information integration.

This paper shows Zip4 directly interacts with Ecm11 to couple crossover formation to synaptonemal complex assembly, preventing excess crossovers.

The paper improves protein-protein interface scoring by integrating atomic-level evolutionary information, achieving higher success rates in docking discrimination.