TAp73 mediates anti-tumor immunity through regulation of lipid metabolism in the lung tumor microenvironment
Hayley D. Ackerman, Vanessa Y. Rubio, Andrew John Davis, John H. Lockhart, Nicole R. Hackel, Rachel V. Jimenez, Rosa A. Sierra-Mondragon, Jaden R Baldwin, Christina Carr, Michelle A. Reiser, Marco Napoli, Xiaoqing Yu, Chia‐Ho Cheng, Paul A. Stewart, Suehelay Acevedo‐Acevedo, , Elsa Renee Flores
This study shows TAp73 regulates lipid metabolism in lung tumor microenvironment to enhance anti-tumor immunity through T-cell activation.
bioRxiv · Nov 21, 2025 · PreprintCancer Biology