EGFR-Driven Phenotypes Dictate Differential Therapeutic Response to Radiotherapy and Temozolomide in Glioblastoma.
María Castelló-Pons, Miguel Perales-Patón, Matteo Italia, Irene Gómez-Soria, Alexis Casero, Juan Belmonte-Beitia, Víctor M. Pérez‐García, Pilar Sanchez-Góméz
This study shows that EGFRwt/amp and EGFRvIII GBM models respond differently to radiotherapy and temozolomide, suggesting EGFR status could guide personalized treatment.
bioRxiv · Nov 22, 2025 · PreprintCancer Biology