Radiopharmaceutical therapy for metastatic prostate cancer: Insights from mechanistic modeling and in silico trials
Matteo Italia, Silvia Bordel-Vozmediano, José García Otero…·Víctor M. Pérez‐García
This paper develops a mechanistic model to simulate [177Lu]Lu-PSMA RPT in mCRPC, using virtual patients to optimize dosing schedules and evaluate efficacy-toxicity trade-offs.