Author

Alexis Klee

University of Rochester Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Chia‐Lung WuiD· 3 shared Eliya Tazreena TashbibiD· 3 shared Eloise FadialiD· 3 shared Gulzada KulzhanovaiD· 3 shared Victoria L. HanseniD· 3 shared Benjamin F. RicciardiiD· 1 shared Brian D. GiordanoiD· 1 shared Deeksha ChintaiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPathology

Chia‐Lung WuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of PRDM16 Drives Nasal Septal Deviation through Dysregulated TGFβ2 Signaling

Eliya Tazreena Tashbib, Victoria L. Hansen, Maeve O'Brien, Alexis Klee, Eloise Fadial, Karin S. Pryharski, Gulzada Kulzhanova, Kathryn Lambright, Lomeli Carpio Shull, Chia‐Lung Wu

This study identifies PRDM16 loss as a driver of nasal septal deviation through TGFβ2 signaling dysregulation in mice.

bioRxiv · Jul 29, 2026 · PreprintDevelopmental Biology

PRDM16 Coordinates Genetic and Epigenetic Programs Governing Chondrogenesis and Chondrocyte Phenotype Specification in the Knee Joint

Eloise Fadial, Victoria L. Hansen, Gulzada Kulzhanova, Eliya Tazreena Tashbib, Deeksha Chinta, Alexis Klee, Helen Shammas, Gourango Pradhan, Chia‐Lung Wu

This study identifies PRDM16 as a critical regulator of chondrogenesis and chondrocyte identity in the knee joint through DNA binding and histone modification.

bioRxiv · Jan 31, 2026 · PreprintPathology

Integrative scRNA-seq and spatial transcriptomics uncovers distinct macrophage-fibroblast cross-talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John E. Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian D. Giordano, Chia‐Lung Wu

In hip osteoarthritis (OA) versus femoroacetabular impingement (FAI) synovium, inflammatory EREG+ lining fibroblasts expand and co-localize more with COL1A1+ fibrotic macrophages; FGF2-SDC4 is their top predicted interaction.

Arthritis & Rheumatology · Jan 12, 2026Peer-reviewedPathology✦ In-depth digest