Author

Gulzada Kulzhanova

University of Rochester MedicineORCID 0009-0000-3946-1275Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alexis Klee· 3 shared Chia‐Lung WuiD· 3 shared Eliya Tazreena TashbibiD· 3 shared Eloise FadialiD· 3 shared Victoria L. HanseniD· 3 shared Benjamin F. RicciardiiD· 1 shared Brian D. GiordanoiD· 1 shared Deeksha ChintaiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersPathology

Alexis Klee

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintJul 29, 2026

Loss of PRDM16 Drives Nasal Septal Deviation through Dysregulated TGFβ2 Signaling

Eliya Tazreena Tashbib, Victoria L. Hansen, Maeve O'Brien…·Chia‐Lung Wu

This study identifies PRDM16 loss as a driver of nasal septal deviation through TGFβ2 signaling dysregulation in mice.

DOI 10.64898/2026.07.28.741259

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PathologybioRxivPreprintJan 31, 2026

PRDM16 Coordinates Genetic and Epigenetic Programs Governing Chondrogenesis and Chondrocyte Phenotype Specification in the Knee Joint

Eloise Fadial, Victoria L. Hansen, Gulzada Kulzhanova…·Chia‐Lung Wu

This study identifies PRDM16 as a critical regulator of chondrogenesis and chondrocyte identity in the knee joint through DNA binding and histone modification.

DOI 10.64898/2026.01.28.701140

𝕏 PostBluesky

PathologyArthritis & RheumatologyPeer-reviewedJan 12, 2026

✦ In-depth digest

Integrative scRNA-seq and spatial transcriptomics uncovers distinct macrophage-fibroblast cross-talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Gulzada Kulzhanova, Alexis Klee, Mina Botros…·Chia‐Lung Wu

In hip osteoarthritis (OA) versus femoroacetabular impingement (FAI) synovium, inflammatory EREG+ lining fibroblasts expand and co-localize more with COL1A1+ fibrotic macrophages; FGF2-SDC4 is their top predicted interaction.

12 citationstop 1%

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