Targeting SCD in SCD-amplified prostate cancer inhibits growth in bone by modulating cellular stress, mTOR, and DNA damage pathways
Alexis Wilson, Mackenzie K. Herroon, Shane Mecca, Laimar C. Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski
This study shows SCD inhibition in prostate cancer reduces tumor growth in bone by affecting cellular stress, mTOR, and DNA damage pathways.
bioRxiv · Jun 9, 2025 · PreprintCancer Biology