Author

Steve M. Patrick

Wayne State UniversityORCID 0000-0003-3325-6750Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jacob Lindquist· 2 shared Alexis Wilson· 1 shared Chris Yunker· 1 shared Istri NdojaiD· 1 shared Izabela PodgorskiiD· 1 shared Joann Sweasy· 1 shared Joshua R. HeyzaiD· 1 shared Laimar C. Garmo· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Jacob Lindquist

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2 papers

Recent·Most cited

Cancer BiologyCancersPeer-reviewedAug 7, 2026

DNA Polymerase Beta Catalytic and Fidelity Mutations Drive Platinum Specific Drug Sensitivity

Jacob Lindquist, Joshua R. Heyza, Istri Ndoja…·Steve M. Patrick

This study identifies Polβ mutations that drive sensitivity to cisplatin and carboplatin in TNBC models, suggesting their use as predictive biomarkers for platinum-based therapies.

DOI 10.3390/cancers18162531

humanDNA methylation

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 9, 2025

Targeting SCD in SCD-amplified prostate cancer inhibits growth in bone by modulating cellular stress, mTOR, and DNA damage pathways

Alexis Wilson, Mackenzie K. Herroon, Shane Mecca…·Izabela Podgorski

This study shows SCD inhibition in prostate cancer reduces tumor growth in bone by affecting cellular stress, mTOR, and DNA damage pathways.

DOI 10.1101/2025.06.09.658523

mouseproteomics

𝕏 PostBluesky