GenomicsScientific ReportsPeer-reviewed
Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration
Gokul Ramaswami, Yeliz Yuva-Aydemir, Brynn N. Akerberg…·David A. Bumcrot
This study assesses iPSC-derived microglia-like cells using bulk and single-cell RNA sequencing, showing they resemble primary human microglia in gene expression and respond to LXR agonists.
14 citations