Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks
Adam J. Rubin, Kevin R. Parker, Ansuman T. Satpathy, Yanyan Qi, Beijing Wu, Alvin J. Ong, Maxwell R. Mumbach, Andrew L. Ji, Daniel Sunwook Kim, Seung Woo Cho, Brian J. Zarnegar, William James Greenleaf, Howard Y. Chang, Paul A. Khavari
Perturb-ATAC combines CRISPR perturbations with single-cell ATAC-seq to identify gene regulatory networks in human cells.
Cell · Dec 20, 2018Peer-reviewedGenomics