Seung Woo Cho

This study identifies MSH2-MSH3's role in promoting DNA end resection during HR and inhibiting TMEJ by interacting with SMARCAD1 and EXO1.

The paper identifies a conserved cell type set in cerebellar nuclei across species and shows how it was duplicated to form new regions, with a shift in dominance in humans.

CRISPRpic provides fast and precise mutation calling by counting exact matches and pattern searches in CRISPR sequencing data.

Perturb-ATAC combines CRISPR perturbations with single-cell ATAC-seq to identify gene regulatory networks in human cells.

This paper uses HiChIP to map enhancer-promoter interactions in primary human cells, linking disease-associated DNA variants to their target genes.

Omni-ATAC improves ATAC-seq by reducing background noise and enabling analysis of frozen tissues, revealing disease-associated DNA element activities in human brain structures.