Early Loss of Deep Restorative Sleep and Auditory Stimulus Evoked 40-Hz activity of Hippocampal Parvalbumin Neurons in the APP/PS1 Mouse Model of Alzheimer's Disease
Fumi Katsuki, James M. McNally, Dmitry Gerashchenko, David S. Uygun, Alyssa Tyler, John G. McCoy, James Timothy McKenna, Ritchie Edward Brown
The paper identifies early loss of deep restorative sleep and 40-Hz activity in hippocampal PV neurons in APP/PS1 mice before cognitive deficits.
bioRxiv · Jul 1, 2026 · PreprintNeuroscience