Ritchie Edward Brown

The paper compares homeostatic sleep responses after two types of wakefulness: gentle handling and optogenetic stimulation of defensive behavior-related neurons, finding distinct sleep recovery patterns.

This study shows that synaptic GABAA receptor dysfunction in thalamocortical neurons disrupts sleep spindle morphology and impairs fear extinction in mice.

The paper identifies early loss of deep restorative sleep and 40-Hz activity in hippocampal PV neurons in APP/PS1 mice before cognitive deficits.

This paper identifies Npas1+ neurons in the basal forebrain as a major GABAergic subpopulation involved in wakefulness and sleep regulation.

The paper identifies individualized temporal patterns as the main determinant of sleep spindle timing in humans, using data from 1008 participants.

Sleep-Deep-Net automates sleep-wake scoring for rodent EEG/LFP data by learning from manual scores provided by users, achieving reliable results across various conditions and reducing manual scoring time to 1/12.

This study characterizes BF vGluT2 neurons, showing they project to arousal-related and aversive stimulus areas and induce avoidance behavior.

The paper tests if basal forebrain parvalbumin neurons modulate vigilant attention in mice using optogenetic methods and finds they improve reaction times and rescue deficits from sleep deprivation.

This study identifies BF parvalbumin neurons as a key component of the brain circuitry mediating brief arousals from sleep in response to internal and external stimuli.