James M. McNally

The paper identifies early loss of deep restorative sleep and 40-Hz activity in hippocampal PV neurons in APP/PS1 mice before cognitive deficits.

This paper identifies Npas1+ neurons in the basal forebrain as a major GABAergic subpopulation involved in wakefulness and sleep regulation.

This study characterizes BF vGluT2 neurons, showing they project to arousal-related and aversive stimulus areas and induce avoidance behavior.

This study examines EEG biomarkers in a genetic mouse model of NMDA receptor hypofunction, finding altered gamma power and sensory gating linked to cognitive impairments.

The paper tests if basal forebrain parvalbumin neurons modulate vigilant attention in mice using optogenetic methods and finds they improve reaction times and rescue deficits from sleep deprivation.

This study identifies BF parvalbumin neurons as a key component of the brain circuitry mediating brief arousals from sleep in response to internal and external stimuli.