Author

Amanda B Abrams

Duke University

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alvin ShiiD· 1 shared Andrea Stewart· 1 shared Brandon T Ruderman· 1 shared Daniel Y. ZhuiD· 1 shared Eric P. SpanaiD· 1 shared Jason C. KleiniD· 1 shared Katharine T. EllisiD· 1 shared Susan P. May· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperDevelopmental Biology

Alvin ShiORCID

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1 paper

Recent·Most cited

speck, first identified in Drosophila melanogaster in 1910, is encoded by the Arylalkalamine N-acetyltransferase (AANAT1) gene

Eric P. Spana, Amanda B Abrams, Katharine T. Ellis, Jason C. Klein, Brandon T Ruderman, Alvin Shi, Daniel Y. Zhu, Andrea Stewart, Susan P. May

This paper identifies the AANAT1 gene as the genetic basis for the speck mutation in Drosophila melanogaster, showing that mutations in AANAT1 lead to the speck phenotype through altered dopamine metabolism.

G3 Genes Genomes Genetics · Jul 24, 2020Peer-reviewedDevelopmental Biology