Developmental BiologyG3 Genes Genomes GeneticsPeer-reviewed
speck, first identified in Drosophila melanogaster in 1910, is encoded by the Arylalkalamine N-acetyltransferase (AANAT1) gene
Eric P. Spana, Amanda B Abrams, Katharine T. Ellis…·Susan P. May
This paper identifies the AANAT1 gene as the genetic basis for the speck mutation in Drosophila melanogaster, showing that mutations in AANAT1 lead to the speck phenotype through altered dopamine metabolism.
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