Author

Amanda Huang

Michigan State UniversityPrimary ORCID profile (0009-0001-9751-7422 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Amanda HuangiD3 papers · Feinstein Institute for Medical Research

Biology Disciplines

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Bioengineering· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aitor AguirreiD· 3 shared Artem M. KiseleviD· 2 shared Brett D. VolmertiD· 2 shared Colin O’HerniD· 2 shared Sammantha Caywood· 2 shared Sang‐Bum ParkiD· 2 shared Aaron H. WassermaniD· 1 shared Aleksandra S. KostinaiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

Aitor AguirreORCID

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3 papers

Recent·Most cited

Self-organizing human heart assembloids with autologous and developmentally relevant cardiac neural crest-derived tissues

Aleksandra S. Kostina, Artem M. Kiselev, Amanda Huang, Haley Lankerd, Sammantha Caywood, Ariadna Jurado-Fernandez, Brett D. Volmert, Colin O’Hern, Aniwat Juhong, Yifan Liu, Zhen Qiu, Sang‐Bum Park, Aitor Aguirre

This paper develops a human heart assembloid model that recapitulates cardiac neural crest integration and reveals antidepressant effects on cardiac development.

bioRxiv · Dec 11, 2024 · PreprintBioengineering

Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions

Colin O’Hern, Sammantha Caywood, Shakhlo Aminova, Artem M. Kiselev, Brett D. Volmert, Fei Wang, Merlinda-Loriane Sewavi, Weiheng Cao, Mia Dionise, Priyadharshni Muniyandi, Mirel Adrian Popa, Hussain F. Basrai, Milana Skoric, George Boulos, Amanda Huang, , Aitor Aguirre

This paper introduces hHMA, a human heart-macrophage assembloid model that integrates autologous cardiac macrophages with heart organoids to study immune-cardiac interactions and disease mechanisms.

bioRxiv · Nov 13, 2024 · PreprintBioengineering

Oxytocin promotes epicardial cell activation and heart regeneration after cardiac injury

Aaron H. Wasserman, Amanda Huang, Yonatan R. Lewis‐Israeli, McKenna D. Dooley, Allison L. Mitchell, Manigandan Venkatesan, Aitor Aguirre

This study shows that oxytocin promotes epicardial cell activation and heart regeneration in both mammals and zebrafish by inducing proliferation, EMT, and migration through the TGF-β pathway.

Frontiers in Cell and Developmental Biology · Sep 30, 2022Peer-reviewedDevelopmental Biology