Author

Amanda J Chen

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Afifa Farooqi· 1 shared Allison C. SharrowiD· 1 shared Apoorva UbovejaiD· 1 shared Emily MegilliD· 1 shared Katherine M. AirdiD· 1 shared Nadine HempeliD· 1 shared Nathaniel W. SnyderiD· 1 shared Naveen Kumar TanguduiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Afifa Farooqi

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1 paper

Recent·Most cited

Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

Allison C. Sharrow, Emily Megill, Amanda J Chen, Afifa Farooqi, Naveen Kumar Tangudu, Apoorva Uboveja, Stacy C. McGonigal, Nadine Hempel, Nathaniel W. Snyder, Ronald J. Buckanovich, Katherine M. Aird

This study shows that ACSS2-mediated acetate conversion to acetyl-CoA promotes quiescence in ovarian cancer cells, linking metabolic reprogramming to therapeutic resistance.

Molecular Metabolism · Sep 19, 2024Peer-reviewedCancer Biology