Author

Allison C. Sharrow

University of PittsburghORCID 0000-0002-4611-6020Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

Apoorva UbovejaiD· 2 shared Katherine M. AirdiD· 2 shared Nadine HempeliD· 2 shared Nathaniel W. SnyderiD· 2 shared Naveen Kumar TanguduiD· 2 shared Ronald J. BuckanovichiD· 2 shared Adam C. SoloffiD· 1 shared Adrian V. LeeiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Apoorva UbovejaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 8, 2025

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis

Raquel Buj, Aidan R. Cole, Jeff Danielson…·Katherine M. Aird

This study shows that zinc availability in the tumor microenvironment affects anti-PD1 therapy response in CDKN2A-low tumors through macrophage phagocytosis.

3 citations

mouseproteomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 15, 2024

Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer.

Santiago Panesso-Gómez, Alexander J. Cole, Alyssa M. Wield…·Ronald J. Buckanovich

This study identifies the MRTFA/SRF pathway as a regulator of quiescence in cancer and shows that inhibiting it induces quiescence and reduces tumor growth.

3 citations

humanscRNA-seq

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Cancer BiologyMolecular MetabolismPeer-reviewedSep 19, 2024

Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

Allison C. Sharrow, Emily Megill, Amanda J Chen…·Katherine M. Aird

This study shows that ACSS2-mediated acetate conversion to acetyl-CoA promotes quiescence in ovarian cancer cells, linking metabolic reprogramming to therapeutic resistance.

11 citations

humanbulk RNA-seq

𝕏 PostBluesky