Author

Amanda M. Honan

University of Miami

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alexander ZaikaiD· 2 shared Clarisel LozanoiD· 2 shared Emily N. VazqueziD· 2 shared Wael M. El-RifaiiD· 2 shared Zhibin CheniD· 2 shared Adam PlattiD· 1 shared Adeeb H RahmaniD· 1 shared Aleksandra WroblewskaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Alexander ZaikaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A ML-framework for the discovery of next-generation IBD targets using a harmonized single-cell atlas of patient tissue

Anoushka Joglekar, Ann Joseph, Pavel Honsa, Klara Ruppova, Veronica Pizzarella, Amanda M. Honan, Devin Mediratta, Emily Vollmer, Evan T. Geller, Martin Valný, Eva Macuchova, Shiwei Zheng, Alisa Greenberg, Petr Tauš, Alina R. Kline-Schoder, , Adeeb H Rahman

The paper develops a machine learning framework to identify cell type-specific gene targets for IBD using a harmonized single-cell atlas and validates them experimentally.

bioRxiv · May 10, 2026 · PreprintBioinformatics

A critical role of epithelial MHCII in initiation of autoimmune tumorigenesis and sustaining premalignancy growth in the stomach

Clarisel Lozano, Emily N. Vazquez, Alexander Kolev, Amanda M. Honan, Wael M. El-Rifai, Alexander Zaika, Zhibin Chen

This study shows epithelial MHCII drives autoimmune tumorigenesis in the stomach by promoting cancer-associated markers and premalignant growth, and its removal reverses early gastric premalignancy.

bioRxiv · Apr 3, 2026 · PreprintImmunology

Autoimmunity and H. pylori infection cooperatively promote epithelial tumorigenic differentiation and systemic immune modulation

Emily N. Vazquez, Clarisel Lozano, Amanda M. Honan, Elena I. Zaika, JeanMarie Houghton, Wael M. El-Rifai, Alexander Zaika, Zhibin Chen

This study shows that autoimmunity and H. pylori infection together promote gastric tumorigenesis and immune suppression in mice.

bioRxiv · Nov 23, 2025 · PreprintCancer Biology