Systematic Engineering of Loss-of-Function Alleles in the Zebrafish Mitochondrial Proteome
Ankit Sabharwal, Md Roushan Ali, K. Mitra, Jun Morisue, Jace Klein, Rishav Sarkar, Kaila S. Savage, Lucy Rai Thulung, Amanda Zumbrock, Cassidy Petree, Santiago Restrepo-Castillo, M. Mota, Gaurav K. Varshney, Karl J. Clark, Eiko Nakamaru‐Ogiso, Stephen Carl Ekker
The paper generates a systematic in vivo atlas of loss-of-function alleles in zebrafish mitochondrial genes, revealing their impact on bioenergetics and hair cell function.
bioRxiv · Sep 17, 2026 · PreprintGenetics