LSD1 demethylase inhibition prevents cardiac fibrosis in both ischemic and congenital diseases in mice and pig models
Arnaud Denis, Virginie Lambert, David Benoîst, Amandine Martin, François Roubertie, Jean Baptiste Gauthier, Michel Pucéat
This study shows that LSD1 inhibitors reduce cardiac fibrosis and improve ventricular function in both mouse and pig models of ischemic and congenital heart diseases.
Cardiology and Cardiovascular Medicine · Jan 1, 2025Peer-reviewedPharmacology & Toxicology