David Benoîst

Sex difference in rat ventilatory response and pulmonary vascular resistance

This study examines sex differences in rat ventilation and pulmonary vascular resistance, finding no sex difference in ventilatory response but higher pulmonary vascular resistance in males.

AI-based identification of cardiac Purkinje fiber cells isolated from whole adult sheep hearts

This paper develops a deep learning-based method to isolate and classify Purkinje fiber cells from adult sheep hearts using imaging data and validation techniques.

LSD1 demethylase inhibition prevents cardiac fibrosis in both ischemic and congenital diseases in mice and pig models

This study shows that LSD1 inhibitors reduce cardiac fibrosis and improve ventricular function in both mouse and pig models of ischemic and congenital heart diseases.

Macrophage-mediated epimorphosis in pig heart with right ventricular failure

The paper shows that cardiac macrophages in pigs with right ventricular failure drive cardiomyocyte de-differentiation and regeneration through epimorphosis.